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Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.334

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_210876560	7.193	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chrX_-_21686079	6.184	NM_014332	SMPX	small muscle protein, X-linked
chr17_-_10500189	5.284	NM_002470	MYH3	myosin, heavy chain 3, skeletal muscle, embryonic
chr10_-_75085754	5.158	NM_001114133	SYNPO2L	synaptopodin 2-like
chr1_-_116112684	5.143		CASQ2	calsequestrin 2 (cardiac muscle)
chr1_-_116112853	5.139		CASQ2	calsequestrin 2 (cardiac muscle)
chr1_-_116112921	4.892	NM_001232	CASQ2	calsequestrin 2 (cardiac muscle)
chr2_-_190635566	4.849	NM_005259	MSTN	myostatin
chr2_+_170074457	4.167	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr10_-_75080784	3.958	NM_024875	SYNPO2L	synaptopodin 2-like
chr12_+_79625538	3.929	NM_002469	MYF6	myogenic factor 6 (herculin)
chr1_-_199657468	3.898	NM_003281	TNNI1	troponin I type 1 (skeletal, slow)
chr1_-_199613427	3.770	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr1_-_199613406	3.767		TNNT2	troponin T type 2 (cardiac)
chr5_+_53787187	3.443	NM_006308	HSPB3	heat shock 27kDa protein 3
chr1_-_151784889	3.106	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr17_-_10265991	2.968	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr20_+_9236446	2.801	NM_000933	PLCB4	phospholipase C, beta 4
chr5_+_155686333	2.692	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr7_+_93862137	2.665		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr6_-_169395847	2.654		THBS2	thrombospondin 2
chr12_-_109842736	2.628	NM_000432	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr5_-_83052606	2.608	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr6_-_169395972	2.575	NM_003247	THBS2	thrombospondin 2
chr2_-_210888010	2.556	NM_079420	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr17_+_42641712	2.494	NM_002476	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr14_-_103058568	2.486		CKB	creatine kinase, brain
chr12_+_118100977	2.302	NM_014365	HSPB8	heat shock 22kDa protein 8
chr3_+_139550368	2.213		MRAS	muscle RAS oncogene homolog
chr3_+_8750485	2.153	NM_033337 NM_001234	CAV3	caveolin 3
chrX_+_70438352	2.129	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr3_+_35696119	2.066	NM_001025068 NM_001025069	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr14_-_103058865	2.011	NM_001823	CKB	creatine kinase, brain
chr21_+_29439768	1.922		C21orf7	chromosome 21 open reading frame 7
chr8_-_122722674	1.916	NM_005328	HAS2	hyaluronan synthase 2
chr5_-_42847716	1.794	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr10_+_91142301	1.789	NM_001548	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr2_+_233206450	1.757	NM_025202	EFHD1	EF-hand domain family, member D1
chr9_+_138991775	1.706	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr4_+_41057507	1.609	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chrX_-_11194015	1.609	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chrX_+_152699616	1.597	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr17_-_10362583	1.562	NM_005963	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr17_+_42641426	1.558	NM_001002841	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr2_+_233206181	1.554		EFHD1	EF-hand domain family, member D1
chr17_+_1612056	1.535		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr13_-_35327798	1.495	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr7_-_143213296	1.494		FAM115A	family with sequence similarity 115, member A
chr2_-_162808123	1.466	NM_004460	FAP	fibroblast activation protein, alpha
chr4_+_169654742	1.367	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr17_+_1612031	1.359		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_+_120276386	1.358	NM_016599	MYOZ2	myozenin 2
chr9_+_96561750	1.348	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr4_-_5881271	1.340		CRMP1	collapsin response mediator protein 1
chr1_+_78243181	1.330	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_+_1611983	1.316	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_-_186934059	1.305	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr1_-_31618405	1.296	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr11_+_1816808	1.258	NM_003282	TNNI2	troponin I type 2 (skeletal, fast)
chr10_+_88418147	1.255	NM_001171610	LDB3	LIM domain binding 3
chr3_-_115825742	1.244	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr21_+_25933459	1.240	NM_021219	JAM2	junctional adhesion molecule 2
chrX_-_138114846	1.206	NM_001139498 NM_001139500 NM_001139501	FGF13	fibroblast growth factor 13
chr17_+_1612092	1.164		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_88418243	1.126	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr3_+_8518539	1.115		LMCD1	LIM and cysteine-rich domains 1
chr11_+_1897374	1.090	NM_001042780 NM_001042781 NM_001042782 NM_006757	TNNT3	troponin T type 3 (skeletal, fast)
chr3_+_139550134	1.076	NM_001085049	MRAS	muscle RAS oncogene homolog
chr11_+_130745580	1.070	NM_001048209	NTM	neurotrimin
chr1_+_144236346	1.067	NM_003637	ITGA10	integrin, alpha 10
chr9_+_99303639	1.061	NM_003275	TMOD1	tropomodulin 1
chr13_+_75232797	1.059	NM_015842	LMO7	LIM domain 7
chr4_-_143987053	0.990	NM_001101669 NM_003866	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_8518508	0.940	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr6_-_26232109	0.932	NM_003526	HIST1H2BG HIST1H2BC	histone cluster 1, H2bg histone cluster 1, H2bc
chr19_-_50514681	0.923		CKM	creatine kinase, muscle
chr8_+_1980564	0.921	NM_003970	MYOM2	myomesin (M-protein) 2, 165kDa
chr1_+_149299530	0.908		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299504	0.900		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr9_+_109131814	0.882		RAD23B	RAD23 homolog B (S. cerevisiae)
chr1_-_202595666	0.882	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr11_+_1817294	0.879	NM_001145829	TNNI2	troponin I type 2 (skeletal, fast)
chr1_+_149299307	0.877		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299490	0.871		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_158352143	0.868	NM_000702	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr12_-_16652202	0.866	NM_001001395	LMO3	LIM domain only 3 (rhombotin-like 2)
chr2_-_189752575	0.864	NM_000393	COL5A2	collagen, type V, alpha 2
chr9_+_99303282	0.864	NM_001166116	TMOD1	tropomodulin 1
chr6_-_24985432	0.863	NM_015864	FAM65B	family with sequence similarity 65, member B
chr4_-_187114407	0.824		SORBS2	sorbin and SH3 domain containing 2
chr17_-_3546108	0.808		P2RX5-TAX1BP3 P2RX5	P2RX5-TAX1BP3 read-through transcript purinergic receptor P2X, ligand-gated ion channel, 5
chr13_-_33148899	0.803		STARD13	StAR-related lipid transfer (START) domain containing 13
chr1_-_201202956	0.789	NM_016243	CYB5R1	cytochrome b5 reductase 1
chr5_-_150501393	0.776	NM_001193544	ANXA6	annexin A6
chr6_+_12825022	0.760		PHACTR1	phosphatase and actin regulator 1
chr10_-_73953699	0.716	NM_001195519	CBARA1	calcium binding atopy-related autoantigen 1
chr19_+_3884100	0.707	NM_170678	ITGB1BP3	integrin beta 1 binding protein 3
chr19_-_20399601	0.700		ZNF826P	zinc finger protein 826, pseudogene
chr7_+_154943466	0.700	NM_001427	EN2	engrailed homeobox 2
chr16_-_31347151	0.694	NM_005205	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr2_+_219991342	0.693	NM_001927	DES	desmin
chr15_-_23204887	0.689	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr1_+_25629968	0.687	NM_018202	TMEM57	transmembrane protein 57
chr8_+_70541412	0.679	NM_001128204 NM_015170	SULF1	sulfatase 1
chr10_-_62373828	0.679	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr1_-_56817717	0.677		PPAP2B	phosphatidic acid phosphatase type 2B
chr8_-_49996353	0.665	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr9_+_123088217	0.659		GSN	gelsolin
chr18_-_3209986	0.651	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr18_+_9698299	0.650		RAB31	RAB31, member RAS oncogene family
chr6_+_131508153	0.634	NM_016377	AKAP7	A kinase (PRKA) anchor protein 7
chr1_+_144149794	0.624	NM_006472	TXNIP	thioredoxin interacting protein
chr10_+_5478521	0.617	NM_005863	NET1	neuroepithelial cell transforming 1
chr22_-_28972683	0.605	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr6_+_26232351	0.602	NM_003512	HIST1H2AC	histone cluster 1, H2ac
chr12_-_16650697	0.600	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_+_60016826	0.599	NM_001164470 NM_017716	MS4A12	membrane-spanning 4-domains, subfamily A, member 12
chr7_-_63660766	0.595		ZNF680	zinc finger protein 680
chr2_-_10505902	0.589	NM_002539	ODC1	ornithine decarboxylase 1
chr19_+_60168463	0.572	NM_001174081	NLRP2	NLR family, pyrin domain containing 2
chr2_+_5750229	0.569	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr10_-_92671005	0.568	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr17_-_26672757	0.564	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr9_+_138991835	0.560		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr2_-_152299229	0.560	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chr12_+_52696908	0.550	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr1_+_154478574	0.542	NM_199173	BGLAP	bone gamma-carboxyglutamate (gla) protein
chr1_+_149298774	0.538	NM_006818	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_10505724	0.537		ODC1	ornithine decarboxylase 1
chr7_+_152087753	0.537	NM_001040135 NM_020445	ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)
chr2_+_108571209	0.533		LIMS1	LIM and senescent cell antigen-like domains 1
chr17_-_74487527	0.533	NM_005567	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein
chr4_-_186970366	0.532	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr9_+_4669557	0.531	NM_017913	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1
chr19_+_23091616	0.530		ZNF730	zinc finger protein 730
chr3_-_139376326	0.526		DBR1	debranching enzyme homolog 1 (S. cerevisiae)
chr17_-_3546236	0.526	NM_002561 NM_175080 NM_175081	P2RX5-TAX1BP3 P2RX5	P2RX5-TAX1BP3 read-through transcript purinergic receptor P2X, ligand-gated ion channel, 5
chrX_+_30171768	0.515	NM_002363 NM_177415	MAGEB1	melanoma antigen family B, 1
chr7_-_63660889	0.511	NM_001130022 NM_178558	ZNF680	zinc finger protein 680
chr12_+_55443358	0.510	NM_003725	HSD17B6	hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
chr9_-_129679760	0.506	NM_000476	AK1	adenylate kinase 1
chr1_+_208568218	0.501	NM_001122834 NM_001170564	HHAT	hedgehog acyltransferase
chr7_+_129693938	0.500	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chr15_+_97990705	0.498	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr6_-_46401363	0.495	NM_005822	RCAN2	regulator of calcineurin 2
chr6_-_152681171	0.482	NM_015293	SYNE1	spectrin repeat containing, nuclear envelope 1
chr13_-_45654327	0.467	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_56817568	0.464		PPAP2B	phosphatidic acid phosphatase type 2B
chr10_-_27097782	0.453		ABI1	abl-interactor 1
chr10_-_69267774	0.447	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_-_116553918	0.444	NM_000493	COL10A1	collagen, type X, alpha 1
chr5_-_111119846	0.443	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr12_+_79634820	0.442	NM_005593	MYF5	myogenic factor 5
chr4_+_70896236	0.431	NM_001009181 NM_003154	STATH	statherin
chr17_-_64752550	0.428	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr1_-_16217025	0.424		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr14_-_101841222	0.422	NM_014226	RAGE	renal tumor antigen
chr19_-_58086410	0.420	NM_207333	ZNF320	zinc finger protein 320
chr13_-_45654296	0.419		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr17_+_7563763	0.415	NM_020877	DNAH2	dynein, axonemal, heavy chain 2
chr3_+_69895651	0.410	NM_006722	MITF	microphthalmia-associated transcription factor
chr15_+_66695932	0.405	NM_001190456	CORO2B	coronin, actin binding protein, 2B
chr5_+_159368690	0.403		TTC1	tetratricopeptide repeat domain 1
chr4_+_169789327	0.402	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr1_-_201321711	0.399		MYOG	myogenin (myogenic factor 4)
chr6_+_12825818	0.395	NM_030948	PHACTR1	phosphatase and actin regulator 1
chr12_-_6535481	0.389	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr2_-_200038055	0.385	NM_001172517	SATB2	SATB homeobox 2
chr7_+_93861808	0.383	NM_000089	COL1A2	collagen, type I, alpha 2
chr13_-_37070862	0.382	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr6_+_27885692	0.376	NM_003536	HIST1H3H	histone cluster 1, H3h
chr4_+_129950222	0.376	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr5_+_159368721	0.373		TTC1	tetratricopeptide repeat domain 1
chr1_+_145892190	0.373	NM_001097616	GPR89C	G protein-coupled receptor 89C
chr5_-_142045770	0.372	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr1_+_242283129	0.366	NM_006352	ZNF238	zinc finger protein 238
chr9_-_21218132	0.362	NM_021268	IFNA17	interferon, alpha 17
chr17_-_38385511	0.362	NM_025267	AARSD1	alanyl-tRNA synthetase domain containing 1
chr2_-_217268492	0.361	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr19_-_60360768	0.359	NM_000363	TNNI3	troponin I type 3 (cardiac)
chr19_+_19872700	0.353	NM_031218	ZNF93	zinc finger protein 93
chr2_+_85619797	0.353	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr13_+_51933228	0.350		CKAP2	cytoskeleton associated protein 2
chr20_-_33463194	0.349	NM_001184977 NM_018244 NM_199487	UQCC	ubiquinol-cytochrome c reductase complex chaperone
chr1_+_201364050	0.344		ADORA1	adenosine A1 receptor
chr1_+_13784553	0.342	NM_001006624 NM_001006625	PDPN	podoplanin
chr7_+_64476167	0.338	NM_007139 NM_152626	ZNF92	zinc finger protein 92
chr2_-_55053398	0.331
chr2_+_108571336	0.330	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chr2_+_38746555	0.330	NM_138801	GALM	galactose mutarotase (aldose 1-epimerase)
chr8_-_120033240	0.328	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr5_+_159368733	0.327	NM_003314	TTC1	tetratricopeptide repeat domain 1
chr5_-_58688428	0.325	NM_001197219	PDE4D	phosphodiesterase 4D, cAMP-specific
chr1_+_65503011	0.323	NM_014787	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_+_6763810	0.323	NM_001142334	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_170370290	0.321		SSB	Sjogren syndrome antigen B (autoantigen La)
chr2_+_172087102	0.321	NM_001127383 NM_024843	CYBRD1	cytochrome b reductase 1
chr11_-_14342627	0.320	NM_001177314	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr5_-_142057692	0.316	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr2_+_85619802	0.315		MAT2A	methionine adenosyltransferase II, alpha

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.44	4.09e-06	GO:0030049	muscle filament sliding
6.44	4.09e-06	GO:0033275	actin-myosin filament sliding
6.27	6.37e-06	GO:0070252	actin-mediated cell contraction
3.12	6.74e-06	GO:0003012	muscle system process
4.98	8.88e-05	GO:0030048	actin filament-based movement
5.73	2.53e-04	GO:0006941	striated muscle contraction
2.53	2.56e-04	GO:0061061	muscle structure development
2.89	5.74e-04	GO:0006936	muscle contraction
2.81	6.52e-04	GO:0007517	muscle organ development
2.40	1.04e-03	GO:0030029	actin filament-based process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.34	1.09e-14	GO:0030016	myofibril
5.01	1.11e-13	GO:0043292	contractile fiber
5.19	2.41e-13	GO:0044449	contractile fiber part
5.54	6.63e-13	GO:0030017	sarcomere
5.03	2.25e-04	GO:0031674	I band
4.96	5.09e-03	GO:0030018	Z disc
11.34	5.73e-03	GO:0005861	troponin complex
1.32	6.76e-03	GO:0043228	non-membrane-bounded organelle
1.32	6.76e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.46	7.94e-03	GO:0005856	cytoskeleton
7.94	1.26e-02	GO:0031672	A band
3.32	1.77e-02	GO:0042383	sarcolemma
12.70	2.31e-02	GO:0031430	M band
2.02	2.43e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.65	2.37e-03	GO:0008307	structural constituent of muscle
1.99	4.26e-02	GO:0003779	actin binding